Vitamin B12 is a fundamental nutrient that gets depleted when dietary intake is inadequate or absorption is impaired. Deficiency in B12 is pervasive in the elderly, vegetarians, and those suffering from malabsorptive issues, such as those caused by acid-blocking medications. Oral consumption of B12 can be as effective as injections, provided enough is taken. Karuna's B-12 Liquid is designed with methylcobalamin, a higher potency than cyanocobalamin that is favored amongst many.