Jarrow Formulas® SAMe 400 offers 400 mg of potent SAMe (net yield) from 800 mg of SAMe tosylate disulfate, carefully manufactured under low temperature and humidity. It's also encased in an enteric coating to ensure maximum activity.
Contains More of the Active S,S Form

Jarrow Formulas® SAMe is a natural, pure metabolite of methionine - an essential amino acid found in all living cells. Carefully produced without chemical solvents, the active (S,S) structure holds 68-80% of the total SAMe content, making it the highest quality available.
SAMe has been clinically shown to have the following benefits:

Joint Strength

SAMe promotes the formation of robust connective tissue through transulfuration.* This process enables the synthesis of glycosaminoglycans (GAGs) such as glucosamine and chondroitin, by sulfating SAMe metabolites to generate sulfated GAGs, such as glucosamine sulfate and chondroitin sulfate.
Brain Metabolism

SAMe methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).*

Liver

SAMe metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase, glutathione reductase and glutathione-S-transferase), which are components of the body’s endogenous antioxidant network and important for liver function, including phase II detoxification.*

Jarrow Formulas® SAMe 400 is foil blister-packed to maximize stability and safety. DO NOT use if outer seal of blister pack is broken.

Full Potency 400 mg SAMe (net yield) is derived from 800 mg of SAMe tosylate disulfate.

For best results, use with Jarrow Formulas® JarroSil®, the biologically Activated Silicon®.