Pregnenolone, sometimes called the "mother steroid," is the natural precursor of all steroid hormones, including androgens, estrogens, corticosteroids, and others. Pregnenolone also acts on GABA receptors in the brain. Oral pregnenolone supports normal psychomotor performance in stressful environments, and may have cognitive and neurosupportive effects as well. Historically, pregnenolone has been used to support joint health.*