Approximately 50% of individuals possess genetic polymorphisms that limit the efficacy of the conversion of folic acid (the most popular form of folate in dietary supplements and fortified foods) to L-methylfolate (the active form of folate) by the enzyme methylenetetrahydrofolate reductase (MTHFR). Thus, for this population, L-methylfolate supplementation is more potent in providing this form of folate. 

• Supports healthy mood, cardiovascular, and nerve function*
• Important for normal production of serotonin, norepinephrine and dopamine*
• Essential for converting homocysteine to methionine*