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C-Plex is a well-documented and effective combination for support of blood lipid and blood sugar levels already in the normal range. High-dose niacin supports blood levels of triglycerides as well as LDL and HDL cholesterol already in the normal range. Inositol hexaniacinate offers an alternative to ordinary niacin because it is a slow-release niacin ester, free from the "niacin flush" and its uncomfortable itching. Chromium supports insulin function, supports blood sugar and blood lipid levels already in the normal range, and is also synergistic with niacin in these actions.*