Berberis Formula contains extracts of barberry, goldenseal, and Oregon grape traditionally used to support GI health. The main bioactive compound in these extracts is berberine, which research shows helps inhibit the adherence of non-beneficial bacteria to the stomach mucosa. It also mediates ion and water transport across intestinal cells, thus promoting electrolyte/water balance.* Berberine boosts expression of the Na+; H+ exchanger and aquaporin, which aid sodium and water absorption.* Additionally, berberine helps ensure proper tight junction formation of intestinal epithelial cells, promoting GI barrier function.* Berberine further stimulates the jejunum through muscarinic receptor activation to support intestinal motility.* 

 

• Traditionally used as a bitter to aid digestion and to help relieve digestive disturbances*
• Includes goldenseal root extract, barberry root and stem extract, barberry root bark, Oregon grape root extract, and Oregon grape root