Methyl B12 (methylcobalamin) is the central form of vitamin B12 active in the body and nervous system. Cyanocobalamin, the form of B12 usually found in supplements, needs to be transformed to methylcobalamin, an often inefficient process. High-dose (1000 mcg or more) methyl B12 supplements conserve bodily resources and ensure enough of this vital form is present to support nerve activity, red blood cell production, energy generation, brain performance, and homocysteine balance.*