Clinically-researched botanicals to support immune, cellular and tissue health*

Perluxan®, a hop extract clinically proven to benefit joint health, was evaluated in a randomized, double-blind, placebo-controlled trial on 36 individuals. Within two hours of the first dose, statistically significant effects were found in joint comfort and this effect was sustained throughout the 14-day period. Additionally, Perluxan® is free of compounds which could cause sleepiness or hormonal changes often found in hops extracts. Alpha and iso-alpha acids in Perluxan® help regulate important pathways related to COX-2 and cytokines like IL-6 and TNFα in connective tissue..

Curcumin C3 Complex® has been observed to significantly influence cytokine-mediated signal transduction, matrix metalloproteinase (MMP) expression, and the arachidonic acid cascade when used in tandem with Perluxan®. Extensive clinical research is being conducted with Curcumin C3 Complex® at a number of universities and hospitals.

Ginger promotes joint health through maintaining healthy cytokine signaling in cartilage and the synovium. 5–LOXIN® Boswellia serrata extract provides the highly bioactive triterpenoid AKBA, which supports connective tissue structural composition and comfort through supporting healthy immune responses, 5-lipoxygenase activity, and synovial matrix metalloproteinase 3 (MMP-3) levels. In a 3-month double-blind, placebo-controlled study of 75 subjects, significant functional support and comfort scores were evident as early as day 7.*

• Supports immune, cellular and tissue health*
• Made with hypoallergenic, vegan ingredients